ANSWER: CBD is short for cannabidiol (pronounced can-uh-bih-DIE-all), one of over 60 compounds called cannabinoids (pronounced kuh-NAB-in-oyds) that are found in the cannabis plant. A number of cannabinoids are produced in the human body as well. Cannabinoids act on receptors found in the cells that are part of the body’s endocannabinoid system, a system that regulates key aspects of our biology. The two major cannabinoid receptors are:
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"The data supporting efficacy and dosing are specific to one product: Epidiolex," Bonn-Miller says. "That's not necessarily translatable to 'Joe Bob's CBD Blend.'" A CBD extract you buy online or in a dispensary will almost certainly have less CBD in it, he explains, and will contain other cannabinoids—meaning that it will work differently and will need to be dosed differently. "This is not to say that 'Joe Bob's CBD Blend' definitely isn't going to be effective for pediatric epilepsy, but it means that we need to study it before we know."
Fortunately for cannabis-curious pet-owners, the spread of legalization across the country is giving doctors enough resources (nerve) to take research into their own hands. In Colorado, Dr. Stephanie McGrath, a neurologist and assistant professor at Colorado State University's College of Veterinary Medicine & Biomedical Sciences, has completed two clinical studies since 2016 on the effects of cannabidiol in dogs with osteoarthritis or epilepsy. In January, the American Kennel Club granted Dr. McGrath $350,000 for her to begin a three-year crossover study of CBD for epilepsy in dogs. Legislation has been proposed in New York and California that would establish guidelines and allow veterinarians to legally discuss the use of cannabis products with their clients.