Jackson Leyden had always been a healthy kid; he practiced taekwondo, and he played lacrosse and baseball. But in 2011, a few months after his eighth birthday, he began having seizures several times a day. Many were brief, a half-minute of staring into space, but he also had severe episodes in which he would collapse, sometimes injuring himself. Over the next two years, he was hospitalized about 50 times, and he missed much of fourth and fifth grade.
Remember: Do not ingest CBD topicals. They should be used externally only. If your skin symptoms have appeared suddenly or if they are very strong and painful, you should first consult your physician before using any supplements or salves. Don't use salves on open, bleeding wounds. Also, do not apply CBD topicals if you are pregnant, lactating, or suffering from a serious illness.
Now 13, Jackson — whose diagnosis is undetermined — continues to use marijuana every day. (Like many patients, he ingests it in droplet form, which allows for more precise dosing and avoids lung problems.) He still has seizures, but they are less severe and they occur once every week or two, down from around 200 a month before he started using cannabis. He is back in school full time and is well enough to go on hikes and bike rides with his family.
CBD oil products are liquid drops of hemp which are taken orally. They are non-psychoactive and are available in low and high concentrations. Hemp oil tinctures are easy-to-use and offer all of the benefits associated with CBD. Hemp oil can be used sublingually via a dropper, or it can be added to your food and beverages which is why most customers have made it their go-to CBD product.
^ Jump up to: a b Devinsky, Orrin; Cilio, Maria Roberta; Cross, Helen; Fernandez-Ruiz, Javier; French, Jacqueline; Hill, Charlotte; Katz, Russell; Di Marzo, Vincenzo; Jutras-Aswad, Didier; Notcutt, William George; Martinez-Orgado, Jose; Robson, Philip J.; Rohrback, Brian G.; Thiele, Elizabeth; Whalley, Benjamin; Friedman, Daniel (22 May 2014). "Cannabidiol: Pharmacology and potential therapeutic role in epilepsy and other neuropsychiatric disorders". Epilepsia. 55 (6): 791–802. doi:10.1111/epi.12631. PMC 4707667. PMID 24854329.
In fact, the law is pretty unclear when it comes to CBD’s state-by-state legality and people (mostly people of color, because a hard-to-interpret law is ripe for racist mishandling) are occasionally charged with possession for carrying CBD. There is a bill in the works (spearheaded by Senator Mitch McConnell, no less) that seeks to get rid of hemp restrictions federally, which would make at least one facet of the law easier to interpret. But TBD on what that means for CBD. So unless you live in a state where marijuana is cleared for recreational use and you’re over the age of 21, the answer to whether or not CBD is legal where you live will vary. And avoid transferring even the most harmless of CBD over state lines. Per Quartz:
CBD primarily interacts with the body’s endocannabinoid system, a grouping of millions of cannabinoid receptors found throughout your body, but are primarily clustered in the brain and central nervous system. While CBD is a phytocannabinoid, or plant-based cannabinoid, your body also naturally produces cannabinoids, known as endocannabinoids. Almost every organ of your body, including your skin and digestive tract, contains cannabinoid receptors. The endocannabinoid system has four primary purposes including neuroprotection, stress relief, immune response, and regulating the body’s general state of balance, impacting faculties such as appetite, sleep, mood, and pain.
For dogs suffering from rashes, skin allergies, arthritis, or other general forms of muscle aches/joint pains (due to old age or otherwise), CBD topicals (salves and creams) are a popular and convenient way to go — they’re reliable, convenient, efficient for acute pain, and for the most part, are super easy to administer (have you ever know a dog that doesn’t love a good rub-down?).
“Research shows that CBD content decreases when it is exposed to heat. It’s likely that the reduction in efficacy is due to the lower content. For instance, studies show that 71 degrees F can accelerate the degradation of CBD in a solution, resulting in less CBD. Potentially adding CBD to hot coffee may degrade it and reduce the amount of CBD available for absorption."
After seasonal harvests of specific cultivars, these high-CBD hemp crops are put through a specialized solvent-free extraction process to yield a hemp oil that is naturally high in cannabidiol. This pure hemp extract is then tested for safety, quality, and cannabinoid content before being exported to our processing facilities in the United States. Importing any cannabis or hemp product into the United States is a complicated and serious task, so we leave nothing to chance before our high-CBD hemp oil makes its journey across the Atlantic Ocean.
Cannabidiol has been found to act as an antagonist of GPR55, a G protein-coupled receptor and putative cannabinoid receptor that is expressed in the caudate nucleus and putamen in the brain. It has also been found to act as an inverse agonist of GPR3, GPR6, and GPR12. Although currently classified as orphan receptors, these receptors are most closely related phylogenetically to the cannabinoid receptors. In addition to orphan receptors, CBD has been shown to act as a serotonin 5-HT1A receptor partial agonist, and this action may be involved in its antidepressant, anxiolytic, and neuroprotective effects. It is an allosteric modulator of the μ- and δ-opioid receptors as well. The pharmacological effects of CBD have additionally been attributed to PPARγ agonism and intracellular calcium release.
I used it on my mother's feet (she's 90). She is great for testing anything because she's in an incredible amount of pain and absolutely NOTHING works for her. Two hours after I applied it, she came into my room and said, "I can't believe that cream actually worked. I still don't have any pain in my toes and the bottom of my feet. It worked so well, I forgot about the pain after you put it on..." Needless to say, she looks forward to an application every evening.
Our hemp extracts may be extremely low in THC, but they are rich in terpenes. Terpenes are organic compounds and isomeric hydrocarbons (C10H16) found within hemp flower excretions. At Bluebird Botanicals, we develop the genetics for our hemp in highly-specialized Colorado greenhouses and source our crops from outdoor farms, which use organic growing methods and no pesticides. These farms cultivate specialty high-terpene hemp plants specifically bred to for the production of hemp and CBD oil.
Generally speaking, most marijuana producers and sellers (especially on the black market) don’t test for contaminants (metals, pesticides, bacteria, etc.). Rick Simpson Hemp Oil is actually more a method of extraction than it is a specific product. People use the Rick Simpson method with hundreds of different strains of marijuana, so the THC, CBD and other cannabinoid content of the final oil always vary greatly, depending on the cannabis the consumers are acquiring. Usually what’s used for Rick Simpson oil is a strain with an inferior CBD content (and high THC), because that’s what the vast amount of marijuana is nowadays.
It depends on your pet and the medicine being used. There have been many examples of dogs being more receptive to PurCBD than traditional medications, especially with anti-seizure, anti-inflammatory, and anti-anxiety medications. Always check with your veterinarian before starting, stopping, or adjusting the dosage of any prescription medication. Many drugs, especially anti-seizure medications, must be weaned off slowly or else deadly withdrawal symptoms can occur.
This peach-hued sea salt soak is the perfect Sunday afternoon bath ritual—and unlike a trendy bath bomb, it won’t turn your tub water a different color. With ingredients like magnesium flakes (stronger than Epsom salts), pink Himalayan salt, arnica, and of course, CBD extract, these crystals provide proactive therapeutic relief while also relaxing your senses with lavender and clary sage essential oils. You can also use them to soak your feet after a long run, just as you would with Epsom salts.
Of course, parents who desperately want to find something—anything—that will help their sick children, don’t have the luxury of caring whether CBD is classified as a drug or a supplement, or whether they get it from a doctor or an online retailer. One reason why people are willing to trust companies like HempMedsPx is that, for some, CBD oil does seem to work.
Carson, too, speculates that CBD might be able to reduce some of the jitteriness associated with caffeine intake, thus complementing it rather than canceling it out. “I can’t say I’ve spent much time in New York, but when I was thinking about talking to you, I got this vision in my head of a stereotypical taxi driver drinking a huge cup of coffee and being really alert but irritable,” he says. “And now if you add in a little CBD, they’re really alert but maybe a little more calm, and not as apt to honk the horn. I think that’s a potential area where there could be something good that comes from adding CBD to the coffee.”
Ingredients: Purified Water, Aloe Barbadensis Leaf Extract, Squalane, Glycerin, Stearic Acid, Cetyl Alcohol, Stearyl Alcohol, Ethylene Glycol Distearate, Menthol, Sodium Acrylates Copolymer, Cannabis Sativa Seed Oil, Arnica Montana Flower Extract, Boswellia Serrata Extract, Allantoin, Propylene Glycol, Phenoxyethanol, Ethylhexylglycerin, Lecithin, Glycerylstereate, Peg 100, Stereate, Diasonilidyl, Tocopherol Acetate
Over the past two years, 17 states have passed laws legalizing CBD so that patients can obtain the drug without fear of prosecution from local authorities. For intractable childhood epilepsies—the sorts of seizure disorders that for centuries have ruined lives and shattered families, the ones even specialists like Hernandez dread—CBD could be a miracle cure.